Medical device and method for manufacturing same

A medical device, comprising:

• a substrate layer;
• and
• a surface lubricious layer formed on at least a part of the substrate layer, the surface lubricious layer containing:
• i) a hydrophilic copolymer that exhibits a lubricating property when in contact with an aqueous liquid, the hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from a group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group;
• and ii) a hydroxy group-containing compound that retains the aqueous liquid to improve lubrication retaining properties of the medical device, the hydroxy group-containing compound being represented by the following formula and being soluble in water,
• the hydrophilic copolymer being present in an amount ranging from 2 parts to 20 parts by weight with respect to 1 part by weight of the hydroxy group-containing compound,
• X—OA-OnY [Chem. 5]
• in the above formula,
• X represents a hydrogen atom or a substituted or unsubstituted monovalent hydrocarbon group having 1 to 22 carbon atoms,
• A represents a group represented by —CH2—, —(CH2)2—, —(CH2)3—, or —CH2—CH(CH3)—,
• n represents a number of 1 or more,
• Y represents a hydrogen atom or an acyl group, and
• when Y represents an acyl group, X represents a hydrogen atom or a monovalent hydrocarbon group having 1 to 7 carbon atoms substituted with a hydroxy group.

A medical device, comprising:

• a substrate layer;
• and
• a surface lubricious layer formed on at least a part of the substrate layer, the surface lubricious layer containing:
• i) a hydrophilic copolymer that exhibits a lubricating property when in contact with an aqueous liquid, the hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from a group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group;
• and ii) a hydroxy group-containing compound that retains the aqueous liquid to improve lubrication retaining properties of the medical device, the hydroxy group-containing compound being selected from a group consisting of glycerol, a glycerol condensate, partially esterified products thereof, and partially etherified products thereof, and being soluble in water,
• the hydrophilic copolymer being present in an amount ranging from 2 parts to 20 parts by weight with respect to 1 part by weight of the hydroxy group-containing compound.