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US 12,582,730 B2Granted
Electroporation devices and methods
AssigneeMayo Foundation for Medical Education and Research
InventorsHideki Ebihara, Jason A. Tri, Kalpathi L. Venkatachalam, Paul A. Friedman, Christopher V. DeSimone, Daniel C. DeSimone, Martin van Zyl, Adetola O. Ladejobi, Andrew D. Badley, Samuel J. Asirvatham
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Abstract
Devices and methods are described for disinfection of pathogenic organisms using pulsed DC field electroporation. For example, this disclosure describes disinfection of pathogenic organisms using pulsed DC field electroporation for lung infection treatment, blood infection treatment, sterilization, and respirators.
Claims8
A system for treatment of lung infections of a patient, the system comprising:
- an endotracheal tube;
- a first electrode that is advanceable along the endotracheal tube;
- a second electrode configured for placement on an exterior chest wall of the patient;
- a source of particulate aerosols, the source configured to introduce the particulate aerosols into airways of the patient via the endotracheal tube;
- a power source configured to deliver energy to the first electrode that causes the first electrode to emit pulse electroporation fields;
- and
- a monitor configured to track airway pressure and to discontinue delivery of energy in response to a change in plateau or peak airway pressures.
4 more elements
Dependencies are inferred from the claim text.