Uses of saccharides from prasinococcales
AssigneeFjord Biotech AS
InventorsCharles Daniel Bavington, Benjamin Dahle, Lars Andreas Dahle, Svein Dahle, Claire Moss
Life of this patent
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Abstract
The present invention relates to a sulphated heteropolymer polysaccharide obtainable from the order of Prasinococcales polysaccharide wherein the average molecular weight of the polysaccharide is between 1,000 and 40,000 kDa, or a fragment of for use in the treatment of skin irritation, wound repair, fibrotic conditions, keloid trait scarring or keloid scars, viral infection, as a biological carrier or scaffold or bio-lubricant; methods of preparing the same and uses thereof, such as in antiviral compositions.
Claims20
A method of treating viral infection, the method comprising:
- administering to a subject in need thereof a composition comprising a polysaccharide having an average molecular weight of between 1,000 and 40,000 kDa, or fragment thereof having an average molecular weight between 5 and less than 1000 kDa, wherein the polysaccharide is a sulphated heteropolymer obtainable from the order of Prasinococcales, and the polysaccharide or fragment thereof has a sulphate content of 17 to 35% by weight.
A method for preparing a wound dressing material, wherein the wound dressing material comprises films of a polysaccharide;
- and the method comprises the steps of:
- preparing an aqueous solution of between 0.01 and 2% by weight (w/v) of the polysaccharide having an average molecular weight between 1,000 and 40,000 kDa or fragment thereof;
- mixing the aqueous solution with a plasticizing agent;
- heating the mixture to a temperature of between 30° C. and 90° C.;
- casting the solution to a thin sheet, optionally of between 2 and 5 mm, by wet or solvent casting;
- and
- drying the thin sheets to form the polysaccharide films;
- wherein
- the polysaccharide having an average molecular weight of between 1,000 and 10 40,000 kDa;
- the polysaccharide fragment having an average molecular weight between 5 and less than 1000 kDa;
- the polysaccharide is a sulphated heteropolymer obtainable from the order of Prasinococcales;
- and
- the polysaccharide or fragment thereof has a sulphate content of 17 to 35% by weight.
A wound dressing material, comprising a polysaccharide having an average molecular weight of between 1,000 and 40,000 kDa, or a fragment thereof having an average molecular weight between 5 and less than 1000 kDa.
- wherein
- the polysaccharide is a sulphated heteropolymer obtainable from the order of 30 Prasinococcales, and the polysaccharide or fragment thereof has a sulphate content of 17 to 35% by weight;
- and
- the wound dressing further comprising a silver sulfadiazine in an amount between 0.05 and 0.25% by weight (w/v).
A method of preparing a carrier device, comprising incorporating a polysaccharide or fragment thereof into a carrier device wherein
- the polysaccharide has an average molecular weight of between 1,000 and 40,000 kDa and the fragment thereof having an average molecular weight between 5 and less than 1000 kDa;
- 30;
- the polysaccharide is a sulphated heteropolymer obtained from the order of Prasinococcales;
- and
- the polysaccharide or fragment thereof has a sulphate content of 17 to 35% by weight.
Dependencies are inferred from the claim text.