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US 12,582,660 B2Granted
Inhibitors of the RAS oncoprotein, methods of making and methods of use thereof
AssigneeUniversity of Louisville Research Foundation, Inc.
InventorsGeoffrey J. Clark, John O. Trent, Joseph A. Burlison
Life of this patent
Estimating the term…
Abstract
A compound for use in treating a disease associated with activating mutations in RAS, or for use in treating a disease treatable by a reduction in RAS activity, is selected from a compound of Formula (I), salts and esters thereof. The compounds are particularly useful in treating cancer.
Claims20
A compound selected from the group consisting of
A method of treating a disease associated with activating mutations in RAS, or treating a disease treatable by a reduction in RAS activity, comprising administering to a patient a compound selected from the group consisting of
Dependencies are inferred from the claim text.