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US 12,582,648 B2Granted
Method for treating central nervous system disorders using dopamine D3 partial agonists
AssigneeBIOPROJET Pharma
InventorsJeanne-Marie Lecomte, Jean Charles Schwartz, Isabelle Berrebi-Bertrand, Stéphane Krief, Xavier Ligneau, Isabelle Lecomte
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Abstract
Disclosed is a method of using D3 partial agonists for treating or inhibiting the restless leg syndrome, binge eating, essential tremor and neurodegenerative diseases, in particular D3 partial agonists/D2 antagonists.
Claims4
A method for treating restless leg syndrome (RLS), comprising administering the compound BP1.4979, of formula:
- N-(4-{2-[4-(3-Cyanophenyl) piperazin-1-yl]ethyl}cyclohexyl)-3-methoxypropanamide or a pharmaceutically acceptable salt thereof, or crystalline structures thereof, comprising administering said compound at a dose comprised between 10 and 15 mg B.I.D. (bis in die).
A method for treating binge eating disorder comprising administering the compound BP1.4979, of formula:
- N-(4-{2-[4-(3-Cyanophenyl) piperazin-1-yl]ethyl}cyclohexyl)-3-methoxypropanamide
- or a pharmaceutically acceptable salt thereof, or crystalline structures thereof.
Dependencies are inferred from the claim text.