Preventive, relief or therapeutic use of 2,3,5-substituted thiophene compound against gastrointestinal stromal tumor
AssigneesPharos Ibio Co., Ltd., Korea Institute of Science and Technology
InventorsTae Bo Sim, Seung Hye Choi, Han Na Cho, Nam Kyoung Kim, Woo Young Hur, Chi Man Song, Ky Youb Nam, Jeong Hyeok Yoon
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Abstract
The present invention relates to the use of a 2,3,5-substituted thiophene compound for the prevention, amelioration or treatment of gastrointestinal stromal tumor. The 2,3,5-substituted thiophene compound exhibits high inhibitory activity against the growth of gastrointestinal stromal tumor, and thus may be effectively used for the prevention, amelioration or treatment of gastrointestinal stromal tumor.
Claims2
A method for treating gastrointestinal stromal tumor caused by substitution of valine for aspartic acid at amino acid position 816 of c-kit protein, comprising the step of administering, to a gastrointestinal stromal tumor patient, a pharmaceutical composition containing a compound represented by the following Formula 1 or a pharmaceutically acceptable salt thereof as an active ingredient:
A method for treating gastrointestinal stromal tumor caused by substitution of valine for aspartic acid at amino acid position 816 of c-kit protein, comprising the step of administering, to a gastrointestinal stromal tumor patient, a compound represented by the following Formula 1 or a pharmaceutically acceptable salt thereof:
Dependencies are inferred from the claim text.