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US 12,582,616 B2Granted
Molecular targets for modulation of dissociative and associative states
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsIsaac V. Kauvar, Sam Vesuna, Karl A. Deisseroth
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Abstract
Methods of treating a subject for a dissociative disorder and methods of screening agents for the ability to modulate dissociative and associative states in a subject are provided. In particular, agents that alter rhythmic neural activity in the posteromedial cortex can be used to modulate dissociative and associative states in a subject.
Claims4
A method of screening a candidate agent to determine if the candidate agent induces or inhibits a dissociative state in a subject, the method comprising:
- a) administering the candidate agent to the subject;
- and
- b) detecting whether the candidate agent induces or inhibits rhythmic neural activity in the posteromedial cortex of the subject.
Dependencies are inferred from the claim text.