Extended release formulations of cannabinoids
AssigneeGlatt GmbH
InventorsReinhard Nowak, Zafar Iqbal, Neha Chavan
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Abstract
Compositions for the extended release of one or more cannabinoids, in which the compositions comprise a population of particles. Each particle may comprise the one or more cannabinoids, one or more drug-releasing agents, one or more surfactants, and a core. The core may comprise a porous bead. The one or more cannabinoids may comprise Δ9-tetrahydrocannabinol, cannabidiol, or a combination thereof.
Claims22
A composition for extended release of one or more cannabinoids, the composition comprising a population of particles, wherein each particle comprises:
- the one or more cannabinoids;
- one or more drug-releasing agents which comprise one or more gel-forming agents;
- a core;
- and
- one or more surfactants;
- wherein the composition releases the one or more cannabinoids over a period of at least 6 hours;
- wherein the core comprises a calcium carbonate bead or calcium phosphate bead;
- wherein the cannabinoids, gel-forming agents, and surfactants form a substantially homogeneous mixture loaded onto the core;
- and
- wherein the particles do not comprise a release-mediating layer external to the mixture.
A composition for extended release of one or more cannabinoids, the composition comprising a population of particles, wherein each particle comprises:
- about 1% to about 20% w/w of the one or more cannabinoids;
- about 5% to about 15% w/w of one or more solubilizers;
- about 15% to about 35% w/w of one or more drug-releasing agents;
- about 20% to about 45% w/w of a core;
- and
- about 15% to about 35% w/w of at least one surfactant,
- wherein the composition releases the one or more cannabinoids over a period of at least 6 hours;
- wherein the core comprises a calcium carbonate bead or calcium phosphate bead;
- wherein the cannabinoids, gel-forming agents, and surfactants form a substantially homogeneous mixture loaded onto the core;
- and
- wherein the particles do not comprise a release-mediating layer external to the mixture.
Dependencies are inferred from the claim text.