Oral care compositions for gum health
AssigneeThe Procter & Gamble Company
InventorsAaron Reed Biesbrock, Yunming Shi, Ross Strand
Life of this patent
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Abstract
An oral care composition with retinoid compound, amino acid, and/or olive oil. An oral care composition with retinoid compound, a pentapeptide, such as palmitoyl KTTKS [SEQ ID NO. 2], and/or an olive oil. Methods of preventing gingival recession, stopping gingival recession, reversing gingival recession, decrease gum recession, increase gingival barrier protection, promoting collagen synthesis, promoting extracellular matrix synthesis, increasing gum resilience, increasing epidermal thickness and/or promoting fibrillin synthesis, in an oral cavity of an animal by contacting the oral care compositions with at least one surface of the oral cavity.
Claims17
A leave-on oral care composition comprising:
- (a) about 0.01% to about 2%, by weight of the composition, of retinoid compound;
- (b) about 0.0001% to about 5%, by weight of the composition, of peptide selected from glycine-histidine-lysine, glycine-glutamic acid-lysine-glycine, lysine-threonine-threonine-lysine-serine, and combinations thereof;
- (c) about 0.01% to about 5%, by weight of the composition, of PEGylated olive oil, wherein the PEGylated olive oil comprises a product of a reaction between olive oil and ethylene oxide;
- and
- (d) a fluoride source,
- wherein the leave-on oral care composition is an emulsion composition and has a yield stress of about 2 Pa to about 250 Pa at 23° C.
A leave-on oral care composition comprising:
- (a) about 0.01% to about 2%, by weight of the composition, of retinol;
- (b) about 0.0001% to about 1%, by weight of the composition, of lysine-threonine-threonine-lysine-serine;
- (c) about 0.01% to about 1%, by weight of the composition, of PEG-7 olive oil carboxylate or a salt thereof;
- and
- (d) at least about 30% water, by weight of the composition, wherein the composition in in the form of a gel having a Viscosity Consistency Coefficient K of 20 Pa's to 500 Pa's as measured at 22° C. at a shear rate range of 0.1-10 s-1 and a Mucoadhesion Index of no less than 0.3 Fluorescent Intensity Percentage.
Dependencies are inferred from the claim text.