Ablation assembly to treat target regions of tissue in organs

An ablation assembly to treat target regions of a tissue in organs comprising:

• an ablation catheter comprising an elongate shaft having a longitudinal main direction (X-X), said elongate shaft comprising at least shaft distal portion, said shaft distal portion comprising a shaft distal portion distal end;
• said ablation catheter comprising an inner lumen arranged within the elongate shaft;
• said ablation catheter comprising a shaft ablation assembly fixedly disposed at said shaft distal portion, the shaft ablation assembly being configured to deliver both thermal energy for ablating said tissue and non-thermal energy for treating said tissue;
• said assembly comprising a distal ablation assembly disposable at least at said shaft distal portion distal end, the distal ablation assembly being configured to deliver both thermal energy for ablating said tissue and non-thermal energy for treating said tissue;
• at least a shape setting mandrel disposed within the ablation catheter, the shape setting mandrel being insertable within the inner lumen and removable from the inner lumen, wherein the shape setting mandrel is free to move in respect of the inner lumen avoiding any constraint with said shaft distal portion during the shape setting mandrel insertion,
• wherein the shape setting mandrel comprises at least a mandrel distal portion, wherein said distal ablation assembly is fixedly disposed at said mandrel distal portion,
• wherein the shape setting mandrel comprises at least a pre-shaped configuration and the shape setting mandrel is reversible deformable between at least a straight loaded configuration and said pre-shaped configuration,
• wherein the shape setting mandrel is slidable outside the shaft distal portion distal end from a mandrel fully inserted position to a mandrel maximum exposed position,
• wherein in said mandrel fully inserted position, the mandrel is in said loaded straight configuration,
• wherein in said mandrel maximum exposed position, the mandrel is in said pre-shaped configuration,
• wherein said mandrel distal portion comprises a mandrel seat, wherein a retention element is fixed to said shape setting mandrel and partially housed in said mandrel seat,
• wherein said inner lumen proximal to said shaft distal portion distal end presents a neck portion,
• wherein said retention element interferes with said neck portion to lock said shape setting mandrel in said mandrel fully inserted position.