Hexokinase 1 isoform B for use as a prognosis marker and specific target against cancer

Double stranded molecules for inhibiting the expression of HK1b isoform when introduced in a cell, comprising a sense strand and an antisense strand, wherein the sense strand comprises a nucleotide sequence corresponding to SEQ ID No:1 and an antisense strand comprises a nucleotide sequence corresponding to SEQ ID No:4, wherein the sense strand comprises a nucleotide sequence corresponding to SEQ ID No:2 and an antisense strand comprises a nucleotide sequence corresponding to SEQ ID No:5, or wherein the sense strand comprises a nucleotide sequence corresponding to SEQ ID No:3 and an antisense strand comprises a nucleotide sequence corresponding to SEQ ID No:6.