Method of producing biochips
AssigneeToray Industries, Inc.
InventorsYoichiro Koshi, Kunihisa Nagino
Life of this patent
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Abstract
A method of biochip production includes a step A of applying a solution containing a selective binding substance, a salt, and a condensing agent to the surface of a substrate, a step B of immobilizing the selective binding substance to the surface of the substrate, a step C of drying the applied solution to allow the salt in the solution to precipitate on the surface of the substrate, and a step D of using an image detection device to detect a precipitate of the salt formed in the step C, wherein, in the step A, the condensing agent in the solution has a concentration of not less than 30 mM and not more than 80 mM.
Claims10
A method of producing a biochip in which a selective binding substance(s) is/are immobilized on a surface of a non-semiconductor substrate plate, the method comprising:
- spotting a solution containing the selective binding substance, a salt, and a condensing agent on the surface of the non-semiconductor substrate plate;
- immobilizing the selective binding substance to the surface of the non-semiconductor substrate plate;
- drying the applied solution to allow the salt in the solution to precipitate on the surface of the non-semiconductor substrate plate;
- and
- detecting a precipitate(s) of the salt formed on the surface of the non-semiconductor substrate plate with an image detection device,
- wherein the condensing agent in the solution applied to the surface of the non-semiconductor substrate plate has concentration of not less than 30 mM and not more than 80 mM.
Dependencies are inferred from the claim text.