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US 12,577,302 B2Granted
Anti-TIM-3 antibodies and compositions
AssigneeLes Laboratoires Servier
InventorsTrine Lindsted, Torben Gjetting, Gunther Roland Galler, Monika Gad, Michael Monrad Grandal, Klaus Koefoed, Michael Kragh, Ivan David Horak, Thomas Bouquin, Mikkel Wandahl Pedersen
Life of this patent
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Abstract
This invention relates to anti-TIM-3 antibodies and antibody compositions and their use in enhancing immunity in a patient, e.g., to treat cancer.
Claims19
An anti-TIM-3 antibody or an antigen-binding portion thereof, wherein said antibody comprises the H-CDR1-3 and L-CDR1-3 amino acid sequences of SEQ ID NOs:
- 40-45, respectively.
An anti-TIM-3 antibody that comprises an HC comprising the amino acid sequences of SEQ ID NOs:
- 38 and 25 or SEQ ID NOs:
- 38 and 5 and an LC comprising the amino acid sequences of SEQ ID NOs:
- 39 and 6.
Dependencies are inferred from the claim text.