5,6-dihydrothieno[3,4-h]quinazoline compound

A compound of formula (P) or a pharmaceutically acceptable salt thereof,

• wherein
• T1 is selected from CR1 and N;
• T2 is selected from CH and N;
• R1 is selected from H;
• R2 is selected from H, CN, C1-3 alkyl, C1-3 alkoxy, C1-3 alkylthiol, S(═O)2C1-3 alkyl, C2-3 alkynyl, C3-5 cycloalkyl, —O—C3-5 cycloalkyl, and 5-membered heteroaryl, and the C1-3 alkyl, C1-3 alkoxy, C1-3 alkylthiol, S(═O)2C1-3 alkyl, C2-3 alkynyl, C3-5 cycloalkyl, —O—C3-5 cycloalkyl, and 5-membered heteroaryl are optionally substituted by 1, 2, or 3 Rb;
• R3 is selected from C1-4 alkyl, piperazinyl, and 7- to 9-membered heterocycloalkyl, and the C1-4 alkyl, piperazinyl, and 7- to 9-membered heterocycloalkyl are optionally substituted by 1, 2, or 3 Rc;
• R4 is selected from C1-3 alkyl and C1-3 alkoxy, and the C1-3 alkyl and C1-3 alkoxy are optionally substituted by 1, 2, or 3 Rd;
• R5 is selected from H and OH;
• or, R1 and R3 together with the atom to which they are attached form a ring, so that the structural moiety
• is selected from
• each Rb is independently selected from F, Cl, Br, I, OH, and OCH3;
• each Rc is independently selected from ═O, C1-3 alkyl, C1-4 alkylamino, and heterocyclobutyl, and the C1-3 alkyl, C1-4 alkylamino, and heterocyclobutyl are optionally substituted by 1, 2, or 3 R;
• each Rd is independently selected from F, Cl, Br, and I;
• each R is independently selected from F, Cl, Br, I, and OH;
• heteroatoms of the “heterocyclobutyl” and “7- to 9-membered heterocycloalkyl” are selected from N, O, and S.