Indoline compound

A compound of formula (I) or a pharmaceutically acceptable salt thereof

• wherein
• ring A is selected from
• L1 and L2 are each independently selected from —CH2— and —CH2—NH—CH2—;
• Z and E are each independently selected from CH and N;
• Z1 selected from O and S;
• Z2 selected from N and CR9;
• X is selected from N and CR14;
• Y is selected from N and CR15;
• R1 selected from H, CH3, and CHF2;
• R2 is selected from CH3 and Cl;
• R3, R4, R5, and R6 are each independently selected from H, C1-6 alkyl, OH, COOH, and —C1-3 alkyl-COOH;
• alternatively, R3, R4 together with the atom to which they are attached form azetidinyl, pyrrolidinyl, oxazolidinyl, or piperidyl, and the azetidinyl, pyrrolidinyl, oxazolidinyl, and piperidyl are each independently and optionally substituted by 1, 2, or 3 R16;
• alternatively, R5, R6 together with the atom to which they are attached form azetidinyl, pyrrolidinyl, oxazolidinyl, or piperidyl, and the azetidinyl, pyrrolidinyl, oxazolidinyl, and piperidyl are each independently and optionally substituted by 1, 2, or 3 R16;
• R7 is selected from H, F, Cl, CH3, and CHF2;
• R8 is selected from —OCH3, —O—CH2—F, and —O—CH2—CN;
• R9 is selected from H, F, and CN;
• R14 and R15 are each independently selected from H and C1-6 alkyl;
• each R16 is independently selected from H, C1-6 alkyl, OH, ═O, COOH, and —C1-3 alkyl-COOH.