Systems and methods for generating nitric oxide

A nitric oxide (NO) delivery system, comprising:

• a NO source for providing a flow of NO-containing gas, the NO source comprising at least one plasma chamber configured to generate a plasma to ionize a reactant gas to generate the NO-containing gas;
• at least one controller configured to communicate with a flow controller to control the flow of the NO-containing gas from the NO source using one or more parameters as an input to the at least one controller;
• and
• a gas sensor pack comprising a manifold having a plurality of sensors attached thereto for measuring a plurality of characteristics of a flow of gas therethrough, the gas sensor pack configured to be removable from a housing of the NO delivery system such that all of the plurality of sensors are replaced simultaneously, the gas sensor pack in communication with the at least one controller to provide information regarding the plurality of measured characteristics,
• wherein the flow of gas through the gas sensor pack is one of a flow of the NO-containing gas and a flow of gas from a patient delivery device.