Hemostatic sponge
AssigneesBaxter International Inc., Baxter Healthcare S.A.
InventorsJoris Hoefinghoff, Hans Christian Hedrich
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Abstract
The present invention provides a hemostatic porous sponge comprising a matrix of a fibrous biomaterial and particles of a fluid absorbing, particulate material adhered to said matrix material, a method of producing these sponges and their use for wound healing.
Claims15
A hemostatic porous sponge having a first, injury-facing side, and an oppositely disposed second side, the hemostatic porous sponge comprising:
- a fibrous biomaterial matrix formed of a fibrous biomaterial comprising gelatin or collagen, the fibrous biomaterial matrix being present in an amount of 1% to 50% of the porous sponge in a dried state (w/w %);
- an adhesive layer continuously coated on the first, injury-facing side of the sponge, the adhesive layer comprising a cross-linkable synthetic polymer comprising succinimidyl groups;
- and
- a supporting layer provided on the second side of the sponge, the supporting layer being an active hemostatic layer having a greater tensile strength than the fibrous biomaterial matrix,
- wherein the sponge is configured to absorb fluid from a site of injury.
A method of treating an injury comprising administering a hemostatic porous sponge to a site of injury, the hemostatic porous sponge having a first, injury-facing side, and an oppositely disposed second side and comprising:
- a matrix of a fibrous biomaterial comprising gelatin or collagen;
- an adhesive layer continuously coated on a first injury facing side of the sponge, the adhesive layer comprising a synthetic polymer comprising succinimidyl groups;
- and
- a supporting layer provided on the second side of the sponge, the supporting layer being an active hemostatic layer having a greater tensile strength than the fibrous biomaterial matrix,
- wherein the sponge is configured to absorb fluid from the site of injury.
A hemostatic porous sponge having a first, injury-facing side, and an oppositely disposed second side, the hemostatic porous sponge comprising:
- a fibrous biomaterial matrix formed of a fibrous biomaterial comprising gelatin or collagen, the fibrous biomaterial matrix being present in an amount of 1% to 50% of the porous sponge in a dried state (w/w %);
- and
- an adhesive layer consisting of a first cross-linkable component and a second cross-linkable component configured to cross-link with the first cross-linkable component under reaction enabling conditions.
Dependencies are inferred from the claim text.