Topical composition
AssigneeFutura Medical Developments Limited
InventorsKenneth William James, James Andrew Provost
Life of this patent
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Abstract
There is provided a composition for topical application to the penis for the treatment of erectile dysfunction, the composition being free of glyceryl trinitrate (GTN), sildenafil and an acetylcholinesterase inhibitor, and comprising volatile and non-volatile solvents, the volatile solvents comprising a lower alcohol and water and the non-volatile solvents comprising a polyhydric alcohol and a glycol. Preferably, the composition does not contain any pharmaceutically active ingredients for the treatment of erectile dysfunction. Also provided is a method of determining the cooling ability of a test composition, such as the composition described above.
Claims11
A composition for topical application to the penis for the treatment of erectile dysfunction, the composition comprising volatile and non-volatile solvents, the volatile solvents comprising a lower alcohol and water and the non-volatile solvents comprising a polyhydric alcohol and a glycol,
- wherein the composition comprises the following amount of ingredients, the ranges being expressed in percentages by weight of the overall composition:
- lower alcohol:
- 30-35%
- water:
- 33-37%
- polyhydric alcohol:
- 22-26%
- glycol:
- 4-8%
- a thickening or gelling agent:
- 0.5-1.5%
- wherein the thickening or gelling agent comprises high molecular weight interpolymers of a crosslinked unsaturated carboxylic acid polymer, which may be a homopolymer or a copolymer, and a copolymeric steric stabiliser having hydrophilic and hydrophobic moieties, and
- wherein the composition does not contain any additional components which are pharmaceutically active ingredients.
A composition for topical application to the penis for the treatment of erectile dysfunction, the composition comprising volatile and non-volatile solvents, the volatile solvents comprising a lower alcohol and water and the non-volatile solvents comprising a polyhydric alcohol and a glycol,
- wherein the composition comprises the following amount of ingredients, the ranges being expressed in percentages by weight of the overall composition:
- lower alcohol:
- 30-35%
- water:
- 33-37%
- polyhydric alcohol:
- 22-26%
- glycol:
- 4-8%
- a thickening or gelling agent:
- 0.5-1.5%,
- wherein the thickening or gelling agent comprises high molecular weight interpolymers of a crosslinked unsaturated carboxylic acid polymer, which may be a homopolymer or a copolymer, and a copolymeric steric stabiliser having hydrophilic and hydrophobic moieties,
- wherein the composition is in the form of a gel and has a pH as manufactured in the range 5.25 to 5.75, and
- wherein the composition does not contain any additional components which are pharmaceutically active ingredients.
Dependencies are inferred from the claim text.