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US 12,576,115 B2Granted
Bacterial compositions for treating and preventing halitosis
AssigneeImvela Corp.
InventorsRaphaël Turcotte, Ravi Sheth
Life of this patent
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Abstract
Some aspects of the disclosure relate to compositions comprising bacterial strains capable of reducing volatile sulfur compounds (VSCs) in an environment, nutritional supplements containing such bacterial strains, and methods of production and use thereof.
Claims18
A nutritional supplement comprising a bacterial mixture and a carrier, the bacterial mixture comprising:
- (i) a first bacterial strain comprising a genome having at least 99.5% average nucleotide identity (ANI) to the genome of SEQ ID NO:
- 18, and which reduces abundance of one or more volatile sulfur compounds (VSCs);
- (ii) a second bacterial strain comprising a genome having at least 99.5% ANI to the genome of SEQ ID NO:
- 19, and which enhances the reduction in abundance of one or more VSCs by the first bacterial strain;
- and
- (iii) a third bacterial strain comprising a genome having at least 99.5% ANI to the genome of SEQ ID NO:
- 20, and which reduces pH of an oral microenvironment of a subject to a value less than 7.5, wherein each of the bacterial strains is lyophilized and in powder form,
- wherein the nutritional supplement has a water content of 5% or less.
5 more elements
Dependencies are inferred from the claim text.