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US 12,576,109 B2Granted
Allogeneic human plasma and platelet derived products and uses thereof
AssigneeConsano Bio, Inc.
InventorsEhab Mosa Alshamleh, Barbara Bennett, Karen Fu, Andrew James Hall, Vishwesh Ashok Patil, Jennifer Louise Schmitke, Teresa Leah Wright, Jennifer Newman, William Kane Grier
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Abstract
Provided herein are compositions comprising allogeneic human plasma and platelet derived product, and methods for making the compositions and using the compositions as a therapeutic for example, in orthopedic indications.
Claims30
A pharmaceutical composition comprising an allogeneic human plasma and platelet derived product, wherein cells and cell debris are removed from the product, wherein the product comprises:
- (a) human plasma proteins comprising human serum albumin, immunoglobulins, and fibrinogen;
- and
- (b) human platelet proteins comprising platelet derived growth factor (PDGF)-AB at a concentration of about 20 ng/ml to about 160 ng/mL,
- wherein the total protein concentration of the composition is greater than 50 mg/mL and less than or about 500 mg/mL.
1 more element
Dependencies are inferred from the claim text.