Dental preparation comprising fibers based on hyaluronic acid with regulated biodegradability

A biodegradable dental preparation in the form of at least one textile unit selected from the group of fibers, a woven, knitted, non-woven or braided fabric, or a twisted bundle of fibers, comprising:

• (A) at least one water-soluble fiber of hyaluronic acid or a physiologically acceptable salt thereof and
• (B) at least one fiber of a non-polar hyaluronic acid derivative according to general formula I:
• wherein R is hydrogen, a physiologically acceptable metal cation, benzyl, or ethyl, and R1 is H or an acyl group selected from capronoyl, capryloyl, caprinoyl, lauroyl, myristoyl, palmitoyl, stearoyl, or oleoyl;
• (C) at least one antimicrobial agent selected from antiseptics, antibiotics and combinations thereof;
• wherein the preparation is in the form of (i):
• a single textile unit which is a fabric or a thread comprising a weight ratio of water-soluble hyaluronic acid fibers to fibers of non-polar hyaluronic acid of general formula I of from 5:95 to 95:5;
• or (ii) a set of at least two textile units,
• wherein the non-polar hyaluronic acid derivative comprises at least one repeating unit comprising at least one substituent R1 that is the acyl;
• and
• wherein the weight average molecular weight of the non-polar hyaluronic acid derivative of general formula I is from 1.0×105 to 1.2×106 g/mol.