Topical, isotonic compositions for genital use
AssigneeGlyciome, LLC
InventorsJoanna E. Ellington, G. D. Clifton, Rayne Ellington-Lawrence
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Abstract
The present disclosure provides compositions and methods for using topical, isotonic compositions comprising a prebiotic oligosaccharide, a metal co-factor, and an essential oil comprising bornyl acetate. The compositions support the genital microbiota and are useful for, for example, hydrating, lubricating, cleaning, and/or decreasing irritation or inflammation of the urogenital and/or anogenital region of a subject, and/or enhancing the beneficial genital microbiota of a subject. Such compositions are useful before, during, and/or after sexual and/or reproductive activity.
Claims14
A topical, isotonic composition comprising:
- (a) about 0.001% to about 5% prebiotic oligosaccharide by weight of the composition, wherein the prebiotic oligosaccharide comprises raffinose, lactulose, trehalose, galactooligosaccharide, alpha-glucan oligosaccharide, beta-glucan oligosaccharide, fructooligosaccharide, isomaltooligosaccharide, maltose, inulin, pectin, or any combination thereof;
- (b) a metal co-factor, wherein said metal cofactor is a metallic ion, or salt thereof, wherein the metal co-factor comprises zinc, selenium, manganese, cobalt, iron, copper, or any combination thereof, and
- (c) an essential oil comprising bornyl acetate, wherein the composition comprises 0.00025% to about 0.15% bornyl acetate by weight of the composition;
- wherein said composition is isotonic with semen and has a pH of about 4.5-6, or
- said composition is isotonic with cervicovaginal fluids and has a pH of about 6-7.
Dependencies are inferred from the claim text.