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US 12,576,092 B2Granted
Pharmaceutical suspensions for bismuth subsalicylates
AssigneeL. Perrigo Company
InventorsInderdeep S. Bhatia, David R. Cassiday, Bruce D. Johnson, Carlos O. Paz
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Abstract
The invention is directed to pharmaceutical compositions for suspending bismuth subsalicylate and methods of use thereof. Formulations of the present invention include at least three-gum systems to prevent the settling out of heavy particles in solution and do not include magnesium aluminum silicate. The pharmaceutical compositions may be used to treat gastrointestinal disorders.
Claims4
A pharmaceutical composition, wherein the composition is a three-gum system, consisting essentially of:
- a) 17.5 mg/mL bismuth subsalicylate;
- b) 2.9 mg/mL xanthan gum;
- c) 1.5 mg/mL hydroxyethyl cellulose;
- and
- d) 17.5 mg/mL a mixture of microcrystalline cellulose and carboxymethyl cellulose.
2 more elements
Dependencies are inferred from the claim text.