Use of varenicline for treating ocular conditions
AssigneeOyster Point Pharma, Inc.
InventorsDouglas Michael Ackermann, Jr., James Loudin, Kenneth J. Mandell
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Abstract
Described herein are methods and pharmaceutical formulations for treating dry eye disease.
Claims29
A method of treating dry eye in a human comprising locally administering a spray of a liquid pharmaceutical formulation comprising between 25 micrograms and 50 micrograms of varenicline into a nostril twice daily, wherein the liquid pharmaceutical formulation comprises varenicline and the concentration of varenicline in the formulation is between about 0.5 mg/mL and about 1 mg/mL.
A method of treating dry eye in a human in need thereof comprising locally administering a spray of a liquid pharmaceutical formulation into a nostril, wherein the formulation comprises varenicline and one or more pharmaceutically acceptable inactive ingredients and the concentration of varenicline in the formulation is between about 0.1 mg/mL and about 10 mg/mL, and wherein the amount of varenicline in the spray is between 5 micrograms and 100 micrograms.
Dependencies are inferred from the claim text.