Liquid pharmaceutical composition
AssigneeFerring International Center S.A.
InventorsBong Gil Nam, Byeung Jun Lee, Shunji Jin
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Abstract
Described are oral, liquid pharmaceutical compositions that include sodium picosulfate, magnesium oxide, citric acid, and malic acid, and methods of making and using such compositions.
Claims20
An oral, liquid pharmaceutical composition, prepared by a process comprising preparing a mixture comprising citric acid, magnesium oxide, malic acid, sodium picosulfate, a pH adjuster, and purified water, wherein the pharmaceutical composition has a pH in the range from 4.1 to 5.4, wherein the sodium picosulfate, magnesium oxide, citric acid, and malic acid are present in a weight ratio of 0.003 to 0.009 sodium picosulfate:1 to 3 magnesium oxide:3.5 to 10.5 citric acid:0.01 to 13 malic acid.
An oral, liquid pharmaceutical composition, comprising citric acid, magnesium oxide, malic acid, sodium picosulfate, sodium hydroxide, disodium edetate, sodium benzoate, and water, wherein the pharmaceutical composition has a pH in the range from 4.1 to 5.4, wherein the sodium picosulfate, magnesium oxide, citric acid, and malic acid are present in a weight ratio of 0.003 to 0.009 sodium picosulfate:1 to 3 magnesium oxide:3.5 to 10.5 citric acid:0.01 to 13 malic acid.
Dependencies are inferred from the claim text.