Use of 2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl) methylidenejinden-1-yl] acetic acid

A method of treating difficult healing various types of wounds and damaged skin in patients with diabetes with a pharmaceutical composition, wherein the composition comprises viscosity enhancers selected from the group consisting of methylcellulose, carboxymethylcellulose, hydroxypropylcellulose, gum arabic, tragacanth, sodium alginate, gelatin, carbomer, bentonite, solvents selected from the group consisting of water, alcohols or glycols, and stabilizers selected from the group consisting of polysorbate and castor oil polyoxyethylene ether or antioxidants selected from the group consisting of pyrosulfate sodium, ascorbic acid, wherein the composition further comprises compound 2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl) methylidene] inden-1-yl] acetic acid of the formula 1 in a unit dose in amount of 1-200 mg in combination with at least one pharmaceutical carrier, wherein

• the method of treatment comprises the following steps:
• every day washing of wounds with 0.05% chlorhexidine solution or any other would disinfectant before treatment procedure to minimize wound contamination and infection,
• applying the pharmaceutical composition in the volume of 200 μl/daily directly on the wound surface,
• applying a sterile gauze for wound covering, and
• washing a chamber cavity with 1 ml of sterile saline 3, 5 and 7 days after wounding under ether anesthesia.