Non-invasive prediction of risk for sudden cardiac death
AssigneeSpangler Scientific LLC
InventorGregory J. Spangler
Life of this patent
Estimating the term…
Abstract
A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk determination is accomplished and may have a sensitivity and specificity of greater than 95%, by generating linear and nonlinear mathematical digital ECG-constructed models from digital ECG-type data of an individual's digital ECG, determining stability/instability of digital ECG-constructed control model systems corresponding to the digital ECG-constructed models by a plurality of techniques and transforming stability/instability values obtained by the determining stability/instability into a quantitative value reflecting an individual's risk for SCD.
Claims18
A method for one or more processors for quantitative determination of a risk associated with ventricular arrhythmia for an individual, the method comprising:
- (a) accessing preprocessed electrocardiogram (ECG)-type data;
- (b) generating a plurality of mathematical digital ECG-derived models corresponding to the preprocessed ECG-type data;
- (c) generating digital ECG-derived control model systems corresponding to each mathematical digital ECG-derived model;
- (d) determining stability of the digital ECG-derived control model systems by applying simulated impulses in a form of perturbations to the digital ECG-derived control model systems, and analyzing results, of the perturbations, that are output by the digital ECG-derived control model systems by calculating stability values with responses to the applying;
- (e) determining, based on the stability values, a derived risk associated with ventricular arrhythmia for the individual;
- and
- (f) outputting the derived risk for display.
A system for quantitative determination of a risk associated with ventricular arrhythmia for an individual, the system comprising:
- one or more processors configured to:
- access preprocessed digital electrocardiogram (ECG)-type data;
- generate a plurality of mathematical digital ECG-derived models corresponding to the preprocessed ECG-type data;
- generate digital ECG-derived control model systems corresponding to each mathematical digital ECG-derived model;
- determine system stabilities of the digital ECG-derived control model systems by applying simulated impulses in a form of perturbations to the digital ECG-derived control model systems, and analyzing results, of the perturbations, that are output by the digital ECG-derived control model systems by calculating stability values with responses to the applying;
- and
- determine, based on the stability values, a derived risk associated with ventricular arrhythmia for the individual;
- and
- generate an output for displaying the derived risk.
A non-transitory storage medium on which instructions are stored, the instructions when executed by one or more processors, cause the one or more processors to perform a method comprising:
- accessing preprocessed electrocardiogram (ECG)-type data for an individual;
- generating a plurality of mathematical digital ECG-derived models corresponding to the preprocessed ECG-type data;
- generating digital ECG-derived control model systems corresponding to each mathematical digital ECG-derived model;
- determining system stabilities of the digital ECG-derived control model systems by applying simulated impulses in a form of perturbations to the digital ECG-derived control model systems, and analyzing results, of the perturbations, that are output by the digital ECG-derived control model systems by calculating stability values with responses to the applying;
- determining, based on the overall stability values, a risk associated with ventricular arrhythmia for the individual;
- and
- generating an output for displaying the risk.
Dependencies are inferred from the claim text.