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US 12,570,643 B2Granted
3-aryloxy-3-five-membered heteroaryl propylamine compound, and crystal form and use thereof
AssigneeShanghai Leado Pharmatech Co. Ltd.
InventorsYouxin Wang, Lingling Zhang, Qiang Ding
Life of this patent
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Abstract
A 3-aryloxyl-3-five-membered heteroaryl propylamine compound, and crystal form and use thereof are provided. Specifically, a compound, or a pharmaceutically acceptable salt or a prodrug thereof, the compound having a structure of formula I is described. The compound, or pharmaceutically acceptable salt or prodrug thereof has an excellent inhibition function for a transient receptor potential channel protein (TPR), and has a good treatment function for diseases associated with the TPR.
Claims10
A crystal form A of the hydrochloride salt of the compound of formula I-1,
- wherein the X-ray powder diffraction pattern of the crystal form A has characteristic peaks at 2θ angles of 18.173±0.2°, 22.084±0.2°, and 22.794±0.2°.
Dependencies are inferred from the claim text.