Use of triazole compound as ghrelin receptor agonist

A method for treating diseases mediated by a ghrelin receptor, wherein the diseases mediated by the ghrelin receptor are selected from the group consisting of eating disorders;

• cancer anorexia or cachexia;
• cachexia or anorexia due to anticancer drugs;
• hyperalgesia due to anticancer drugs;
• chronic obstructive pulmonary disease (COPD) or COPD cachexia;
• sarcopenia;
• weight loss;
• generalized weakness after surgery in cancer patients;
• chronic airway infection;
• inflammation;
• inflammatory bowel disease (IBD);
• functional dyspepsia (FD);
• constipation;
• diabetic gastroparesis;
• heart failure;
• myocardial infarction;
• diabetic neuropathy;
• growth hormone deficiency;
• defecation disorders in patients with spinal injuries;
• postoperative ileus;
• anoxia;
• and morphine-induced intestinal obstruction,
• comprising administering an effective amount of a composition comprising a compound of the following Formula 1 or a pharmaceutically acceptable salt thereof to a subject in need thereof:
• wherein
• R1 is hydrogen;
• straight or branched chain alkyl having 1 to 15 carbon atoms;
• or substituted or unsubstituted alkylcarbonyl having 1 to 5 carbon atoms, and R2 is hydrogen;
• straight or branched chain alkyl having 1 to 15 carbon atoms;
• alkenyl having 2 to 10 carbon atoms;
• or alkynyl having 2 to 10 carbon atoms.