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US 12,570,599 B2Granted
Process for preparing acyl-capped 3-hydroxycarboxylic acids and their salts and esters
AssigneeKetoLipix Therapeutics GmbH
InventorsDirk Lochmann, Sebastian Reyer, Michael Stehr
Life of this patent
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Abstract
The invention relates to a method for producing optionally functionalized acyl-capped (acyl-blocked) 3-hydroxybutyric acids and their salts and esters as well as to the products thus obtained and their use.
Claims8
A functionalized acyl-capped 3-hydroxybutyric ester,
- wherein the functionalized acyl-capped 3-hydroxybutyric ester corresponds to general formula (III″)
- CH3—CH(OR3)—CH2—C(O)OR4 (III″)
- wherein, in the general formula (III″), the radical R3 represents a radical CH3—C(O)—CH2—C(O)— and the radical R4 represents a linear or branched, saturated or mono- or polyunsaturated aliphatic C6-C30-alkyl radical.
A functionalized acyl-capped 3-hydroxybutyric ester,
- wherein the functionalized acyl-capped 3-hydroxybutyric ester corresponds to general formula (III″)
- CH3—CH(OR3)—CH2—C(O)OR4 (III″)
- wherein, in the general formula (III″), the radical R3 represents a radical CH3—C(O)—CH2—C(O)— and the radical R4 represents a linear or branched, saturated or mono- or polyunsaturated aliphatic C10-C30-alkyl radical.
Dependencies are inferred from the claim text.