Microfluidic devices

A multilayer microfluidic device configured to sample, meter and collect a metered volume of body fluid for analysis by means of capillary transport, wherein the device comprises:

• an inlet section for receiving a body fluid sample, and a flat, laterally extending filtration membrane, wherein the inlet section comprises an inlet port and is configured to transport and access the sample to the filtration membrane;
• a metering section, comprising an extraction chamber and a metering channel, the extraction chamber being configured to receive an extracted body fluid from the filtration membrane and arranged in fluid communication with the metering channel;
• and
• an outlet section configured to receive and collect a metered volume of body fluid from the metering channel, the outlet section comprising a capillary means for collection of the metered volume of body fluid,
• wherein a roof of the extraction chamber is defined by a flat lower surface of the filtration membrane, and a floor of the extraction chamber is continuous with a floor of the metering channel and extends at an acute angle from the lower surface of the filtration membrane,
• wherein the floor of the extraction chamber is inclined with respect to the floor of the metering channel to create a slope, and
• wherein the extraction chamber is wedge-shaped with the floor and roof of the extraction chamber diverging from each other in a direction towards the metering channel.