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US 12,569,820 B2Granted
Universal functionalized beads and method of making same
AssigneeRAN Biotechnologies, Inc.
InventorsRobert E. Lintner, Roger A. Nassar
Life of this patent
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Abstract
The present invention is generally directed to beads, methods of making said beads, and methods of functionalizing said beads with one or more functional groups to form functionalized beads, such as universal functionalized beads, wherein the functional group can be a chemical group. In some embodiments, the beads can be gel beads.
Claims16
A method of making gel beads, the method comprising:
- suspending a first fluid sample in a second fluid sample to form a plurality of fluidic droplets, wherein the first fluid sample comprises a plurality of first species;
- and
- gelating the fluidic droplets to form a plurality of first gel beads comprising the first species, wherein one or more of the first species have one or more chemical functionalities,
- suspending the first gel beads in a third fluid sample comprising a plurality of second species;
- and
- reacting the one or more of the plurality of first species that have one or more chemical functionalities with one or more of the plurality of second species to functionalize the first gel beads with the one or more second species,
- wherein the one or more chemical functionalities are non-biological functionalities.
4 more elements
Dependencies are inferred from the claim text.