Raw-material liquid concentration system and concentration apparatus
AssigneeAsahi Kasei Kabushiki Kaisha
InventorsTomotaka Hashimoto, Yuki Suga
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Abstract
This raw-material liquid concentration system is for use in a pharmaceutical product manufacturing process, and employs a membrane-distillation method involving: bringing a raw-material liquid containing a solvent and a solute into contact with cooling water through a membrane-distillation membrane; passing the solvent in the raw-material liquid through the membrane-distillation membrane in the form of vapor; and causing the solvent to move toward the side of the cooling water, wherein the membrane-distillation membrane is a porous membrane that has a water contact angle of at least 90° at the surface thereof, has an average pore diameter of 0.02-0.5 μm, and has a porosity of 60-90%.
Claims14
A feed solution concentration system for a drug manufacturing process, the feed solution concentration system comprising a distillation membrane apparatus in which a feed solution containing a solvent and a solute is brought into contact with cooling water via a membrane in the distillation membrane apparatus and the solvent in the feed solution is passed through the membrane as a vapor and moved to the cooling water side,
- wherein the membrane is a porous membrane and has a surface water contact angle of 90° or greater, an average pore size in a range of 0.02 μm or greater and 0.5 μm or less, and a porosity of 60% or greater to 90% or less,
- a hydrophobic polymer is attached to at least a portion of the membrane and is present on both sides of the membrane, and
- the hydrophobic polymer has an adhesion amount with a distribution in a thickness direction of the membrane, and the adhesion amount on a surface layer of at least one side of the membrane is larger than an adhesion amount of an inner portion.
A concentration apparatus for concentrating a feed solution by membrane distillation, the concentration apparatus comprising a membrane for membrane distillation,
- wherein the membrane has a membrane surface water contact angle of 90° or greater, an average pore size in a range of 0.02 μm or greater and 0.5 μm or less, and a porosity of 60 to 90%,
- a hydrophobic polymer is attached to at least a portion of the membrane and is present on both sides of the membrane, and
- an adhesion amount of the hydrophobic polymer has a distribution in a thickness direction of the membrane, and an adhesion amount to a surface layer of at least one side of the membrane is larger than an adhesion amount to an inner portion.
Dependencies are inferred from the claim text.