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US 12,569,539 B2Granted
Adipocytes over-expressing FFAR4 and use thereof
AssigneesNumt Inc., Toho University
InventorsYoshinori Takei, Akira Hirasawa
Life of this patent
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Abstract
Provided herein is a method for treating and/or preventing various diseases including a decrease in glucose tolerance and a decrease in cognitive ability associated with aging with adipocytes over-expressing FFAR4 and a transplant composition including the adipocytes.
Claims7
A method for treating a decrease in cognitive ability associated with aging, comprising:
- transplanting a transplant composition into a human or an animal, wherein the transplant composition comprises an adipocyte modified to express FFAR4 by introducing a gene encoding FFAR4 into the adipocyte, thereby treating the decrease in cognitive ability associated with aging.
A method for delaying a decrease in cognitive ability associated with aging, comprising:
- transplanting a transplant composition into a human or an animal, wherein the transplant composition comprises an adipocyte modified to express FFAR4 by introducing a gene encoding FFAR4 into the adipocyte, thereby delaying the decrease in cognitive ability associated with aging.
Dependencies are inferred from the claim text.