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US 12,569,528 B2Granted
Methods for making botanical extract composition
AssigneeCargill, Incorporated
InventorsSkye Doering, Dan S. Gaspard, Kristopher T. Mortenson, Adam T. Zarth
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Abstract
A method for making a caffeoylquinic composition from a botanical source is disclosed. The method may include chromatographing an extract of biomass on an ion exchange stationary phase and obtaining an eluent comprising a caffeoylquinic composition. The biomass may be stevia or yerba mate, for example. The caffeoylquinic composition includes one or more of monocaffeoylquinic acid, dicaffeoylquinic acid, and salts of the foregoing.
Claims11
A method for making a caffeoylquinic composition, the method comprising:
- i) contacting yerba mate biomass, stevia biomass, or combinations thereof with a first aqueous composition comprising less than 30% (C1-C4) alkanol or free of (C1-C4) alkanol to obtain an initial extract;
- ii) chromatographing the initial extract on an ion exchange stationary phase;
- and
- iii) eluting the stationary phase with an acidified aqueous elution composition comprising 20% to 50% (C1-C4) alkanol to obtain the caffeoylquinic composition,
- wherein the caffeoylquinic composition comprises one or more of monocaffeoylquinic acid, dicaffeoylquinic acid, and salts of the foregoing;
- wherein the caffeoylquinic composition comprises less than 1% by weight of caffeine or rutin based on dry weight of the caffeoylquinic composition, and wherein the caffeoylquinic composition has a percent transmittance at 430 nm of greater than 80% without a decoloring or desalting step following step (iii).
3 more elements
Dependencies are inferred from the claim text.