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US 12,569,470 B2Granted
Vasodilator and use thereof
AssigneeBioradical Research Institute Corp.
InventorMasaichi Lee
Life of this patent
Estimating the term…
Abstract
The present invention provides a vasodilator capable of dilating a blood vessel even in the presence of ROS. A vasodilator of the present invention includes: a compound represented by the following formula (1) or a salt thereof: where in the formula (1), an A ring and a B ring may be the same or different and are each a pyrazole ring having a substituent or a pyrazoline ring having a substituent, and L is a saturated or unsaturated hydrocarbon group.
Claims17
A vasodilation method using a vasodilator, wherein the vasodilator comprises:
- a compound represented by the following formula (1) or a salt thereof:
- where in the formula (1),
- an A ring and a B ring may be the same or different and are each a pyrazole ring having a substituent or a pyrazoline ring having a substituent, and
- L is a saturated or unsaturated hydrocarbon group,
- the method comprising administering the vasodilator to a patient with a disease caused by vascular stenosis, and
- the disease caused by vascular stenosis is hematological disease, cardiovascular disease, central nervous system disease, digestive system disease, respiratory system disease, urological disease, or dental disease.
3 more elements
A method for treating a disease caused by vascular stenosis, the method comprising:
- administering to a patient a compound represented by the following formula (1) or a salt thereof:
- where in the formula (1),
- an A ring and a B ring may be the same or different and are each a pyrazole ring having a substituent or a pyrazoline ring having a substituent, and
- L is a saturated or unsaturated hydrocarbon group, and
- the disease caused by vascular stenosis is hematological disease, cardiovascular disease, central nervous system disease, digestive system disease, respiratory system disease, urological disease, or dental disease.
2 more elements
Dependencies are inferred from the claim text.