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US 12,566,185 B2Granted
Blood coagulation time measurement method
AssigneeSekisui Medical Co., Ltd.
InventorToshiki Kawabe
Life of this patent
Estimating the term…
Abstract
Provided is a method for accurately measuring coagulation time of blood samples showing various coagulation reactions. The method for measuring blood coagulation time includes measuring coagulation reaction of a sample prepared by mixing a subject specimen and a coagulation time measurement reagent; calculating weighted average time of a calculation target area of a waveform related to coagulation velocity from the resulting measurement data; and determining the weighted average time as blood coagulation time.
Claims7
A method for measuring blood coagulation time, comprising:
- measuring coagulation reaction of a sample prepared by mixing a subject blood specimen and a coagulation time measurement reagent to obtain measurement data;
- calculating weighted average time of a first order differential curve of a coagulation reaction curve from the obtained measurement data;
- and
- determining the weighted average time as blood coagulation time of the subject blood specimen, wherein
- the weighted average time is represented by a following equation, where F(t), wherein t is time, is the first-order differential curve of the coagulation reaction curve, and t1 and t2, wherein t1<t2, are times when F(t) is x %, wherein x is a prescribed value set within a range of 5 to 95, of the maximum value of F(t):
- Weighted
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43 more elements
Dependencies are inferred from the claim text.