Phospholipid
AssigneeNippon Fine Chemical Co., Ltd.
InventorsKoji Tomita, Yuki Inoue, Ayano Yokouchi, Sae Asayama, Naofumi Fukata
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Abstract
The present invention provides a charge-reversible phospholipid that is not positively charged at a pH of the body fluid (typically in the neutral range) and has low cytotoxicity. The present invention provides a phospholipid represented by formula (1): wherein m represents a natural number of 9 to 25, n represents a natural number of 10 to 15, X1, X2, and X3 are the same or different and each represent H or OH, and R1 represents the following formula (i) or (ii): wherein p represents 1 or 2, q represents 1 or 2, and r represents an integer of 1 to 4; or wherein s represents an integer of 1 to 3, and R2 represents a hydrogen atom or a hydrocarbon group.
Claims12
A phospholipid represented by formula (1):
- wherein m represents a natural number of 9 to 25, n represents a natural number of 10 to 15, X1, X2, and X3 are the same or different and each represent H or OH, and R1 represents the following formula (i) or (ii):
- wherein p represents 1 or 2, q represents 1 or 2, and r represents an integer of 1 to 4;
- or
- wherein s represents an integer of 1 to 3, and R2 represents a hydrogen atom or a hydrocarbon group.
Dependencies are inferred from the claim text.