US 12,565,480 B2 · Thiophene derivatives as xanthine oxidase inhibitors and application thereof

Abstract

A class of xanthine oxidase (XO) inhibitors, and application thereof in the preparation of drugs for treating XO-related diseases. Specifically disclosed is a compound represented by formula (I) and a pharmaceutically acceptable salt thereof.

Claims6

Dependent claims

A compound represented by formula (I) or a pharmaceutically acceptable salt thereof,

wherein,
R2 is OH;
and
the structural unit
is selected from the group consisting of

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

17/766,435Filed 30 Oct 2020

Priority

CN 201911049951.730 Oct 2019

Published

US 2023/0322703 A112 Oct 2023

Granted

3 Mar 2026

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07D 333/70
Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen: attached in position 2
A61K 31/381
Having sulfur as a ring hetero atom: having five-membered rings
A61P 19/06
Drugs for skeletal disorders: antigout agents, e.g. antihyperuricemic or uricosuric agents
C07D 495/04
In which the condensed system contains two hetero rings: ortho-condensed systems

Abstract

Claims6

Dependent claims

A compound represented by formula (I) or a pharmaceutically acceptable salt thereof,

wherein,
R2 is OH;
and
the structural unit
is selected from the group consisting of

2 more elements

Dependencies are inferred from the claim text.

Thiophene derivatives as xanthine oxidase inhibitors and application thereof

Life of this patent

Abstract

Claims6

Thiophene derivatives as xanthine oxidase inhibitors and application thereof

Life of this patent

Abstract

Claims6