Tumor radiotherapy planning design method and apparatus, electronic device and storage medium

A tumor radiotherapy planning design method, comprising:

• obtaining an initial optimization parameter vector set as a current optimization parameter vector set, and calculating a current cost function value;
• randomly correcting the current optimization parameter vector set to generate a preset number of alternative optimization parameter vector sets;
• performing planning parameter optimization based on the preset number of alternative optimization parameter vector sets, and calculating a total cost function value for each of the preset number of alternative optimization parameter vector sets by a multifunctional optimization total cost function, wherein the multifunctional optimization total cost function is obtained as follows:
• tot=λ·acc+qlt
• where tot represents the multifunctional optimization total cost function, acc represents a plan delivery accuracy cost function, qlt represents a plan dosimetric quality cost function, λ represents a relative weight factor between the plan delivery accuracy cost function and the plan dosimetric quality cost function, and λ is in a range of 10.0 to 30.0;
• determining current optimal or suboptimal alternative optimization parameter vector sets according to the total cost function values of the preset number of alternative optimization parameter vector sets, sampling to update the current optimization parameter vector set and the current cost function value according to the total cost function values of the current alternative optimization parameter vector sets, and then performing an iteration repeatedly until a convergence condition is satisfied;
• outputting an optimal optimization parameter vector set after the iteration, determining planning parameters, and calculating and outputting planning multi-leaf collimator (MLC) leaf positions and dose distributions according to the planning parameters to thereby obtain a tumor radiotherapy plan of a patient, wherein the tumor radiotherapy plan contains the planning MLC leaf positions and the dose distributions;
• and
• performing experimental measurement on the tumor radiotherapy plan through a radiation detector array to obtain a measurement result, analyzing a gamma passing rate (GPR) of the measurement result, and performing, when the GPR of the measurement result is greater than or equal to 90%, treatment on the patient based on the tumor radiotherapy plan to facilitate curing the patient.