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US 12,564,660 B2Granted
Biofabrication of vaginal support using vaginally derived cells
AssigneeMagee-Womens Research Institute & Foundation
InventorsPamela Moalli, Vivian Sung, Jeffrey Morgan
Life of this patent
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Abstract
Embodiments relate to a living tissue graft derived from autologous cells used to provide support or to strengthen/reinforce compromised tissue. The living tissue graft comprises both cells and extracellular matrix (ECM) and overcomes problems related to foreign body responses to synthetic materials and rejection reactions to allograft tissue.
Claims10
A method for treating damaged tissue, said method comprising replacing or augmenting the damaged tissue by the steps of:
- preparing a living tissue graft derived from said damaged tissue;
- and
- implanting, transplanting, administering, applying, adhering or affixing the living tissue graft onto the damaged tissue,
- wherein the step of preparing the living tissue graft comprises:
- preparing a plurality of subunits comprising cells isolated from the damaged tissue and extracellular matrix;
- fusing the plurality of subunits to form a plurality of microtissue units;
- and
- assembling the plurality of microtissue units to form the living tissue graft.
5 more elements
Dependencies are inferred from the claim text.