Compositions, formulations, and methods for skin treatment

A method for treating a skin condition, disorder, or disease, the method comprising administering to a subject in need thereof a composition comprising a compound having a structure of Formula (V):

• or a salt thereof, wherein:
• Y1 is O or NR1, wherein R1 is H, alkyl, or haloalkyl;
• R2 is selected from H, alkyl, haloalkyl, alkenyl, haloalkenyl, aryl, and aralkyl;
• and
• R3 is selected from H, alkyl, haloalkyl, —(CH2)m1—ORa1, —(CH2)m2—O—(CH2)m3—ORa2, (CH2)m5—C(O)ORc,
• wherein:
• Ra1, Ra2, and Rc are each independently selected from H, alkyl, and haloalkyl;
• and
• m1, m2, m3, and m5 are each independently selected from 1, 2, 3, and 4.