Reversible occlusion device, system and method

A reversible occlusion device configured for being introduced inside a lumen to selectively occlude said lumen, said reversible occlusion device comprising a docking unit configured for being docked in the lumen and having, at least when positioned the lumen, an upstream end associated with an upstream portion of the lumen, and a downstream end associated with a downstream portion of the lumen, and an inner volume extending between a first opening at said upstream end, and a second opening at said downstream end, said reversible occlusion device further comprising at least one restricting element configured for transitioning, at least once, between a first, closed position, in which said restricting element obstructs passage of material across said volume between said first opening and said second opening, and a second, open position, in which said restricting element allows passage of material across said volume between said first opening and said second opening, wherein in both said closed position and said open position, a peripheral portion of said restricting element is in contact with said docking unit, wherein said restricting element is in the form of a membrane having a variable thickness, wherein a peripheral portion of the membrane, located closer to the docking unit, has a first thickness t1, and wherein a central portion of the membrane, closer to the longitudinal axis of the reversible occlusion device, has a second thickness t2<t1.