Modular, configurable bioreactor system for a manufacturing line

A system for repeatably performing at least one type of tissue-related process as part of a manufacturing line, the system comprising:

• at least one variably-sized culture vessel including a vessel sleeve surrounding at least a section of the at least one variably-sized culture vessel, the vessel sleeve configured to transfer thermal energy to the at least one variably-sized culture vessel, a thermal sleeve operably coupled with the vessel sleeve, the thermal sleeve controlling an amount of thermal energy entering the vessel sleeve;
• and a vessel clamp stabilizing the at least one variably-sized culture vessel within the thermal sleeve;
• a fluid handling system including at least one pump, at least one valve and at least one sensor, the fluid handling system moving fluid through said at least one variably-sized culture vessel;
• a culture vessel controller, controlling said fluid handling system by monitoring said at least one sensor and adjusting said at least one valve to maintain setpoints within said at least one variably-sized culture vessel perform the at least one type of tissue-related process;
• a gas management system providing at least one type of gas to the at least one variably-sized culture vessel;
• and
• at least one controller monitoring the status of culture vessel controller and scheduling the at least one type of tissue-related process as between components on the manufacturing line using a standard industrial communications protocol.