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US 12,559,572 B2Granted
Compositions and methods for treating IgE-mediated disorders
AssigneeXencor, Inc.
InventorsJohn R Desjarlais, Seung Y. Chu, Holly M. Horton, Matthew J. Bernett
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Abstract
The present invention relates to immunoglobulins that bind IgE and FcγRIIb with high affinity, said compositions being capable of inhibiting cells that express membrane-anchored IgE. Such compositions are useful for treating IgE-mediated disorders, including allergies and asthma.
Claims1
An antibody comprising:
- a heavy chain comprising SEQ ID NO:
- 17;
- and
- a light chain comprising SEQ ID NO:
- 21.
2 more elements
Dependencies are inferred from the claim text.