NPY2 receptor agonists
AssigneeBoehringer Ingelheim International GmbH
InventorsPeter Wilhelm Haebel, Albert Brennauer, Charlotte Stahl Madsen, Soren Ljungberg Pedersen, Stefan Peters
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Abstract
The invention relates to PYY analogues having alanine at position 4, lysine at position 7, QRY as the C-terminal end and a half-life extending group. The analogues of the invention are soluble around pH 6 and 7. The invention also relates to pharmaceutical compositions comprising such PYY analogues, and to the medical use of the analogues.
Claims8
A method of preventing weight gain or promoting weight loss in an individual in need thereof, said method comprising administering a therapeutically effective amount of a compound comprising
- or a pharmaceutically acceptable salt thereof, to the individual.
A method of treating a condition caused or characterized by excess body weight in an individual in need thereof, said method comprising administering to the individual a therapeutically effective amount of a compound comprising
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.