Systems, devices, and methods for aspirating biological material from a body lumen

An intraluminal system for aspirating biological material from a lumen of a patient, comprising:

• a disposable intraluminal device comprising a distal portion configured to be positioned within the lumen of the patient and a proximal portion in fluid communication with the distal portion and positioned outside of the patient;
• and
• a disposable pump configured to aspirate the biological material from the lumen of the patient, the disposable pump coupled to the proximal portion of the intraluminal device and comprising a pump chassis that houses:
• an inlet port configured to sealably attach to the proximal portion of the intraluminal device;
• an outlet port configured to expel the aspirated biological from the pump;
• a flow controller configured to adjust a fluid flow through the pump;
• an actuator;
• a first pump chamber;
• a second pump chamber separate from the first pump chamber;
• and
• a dual displacement adapter coupled to the actuator such that the actuator is configured to drive the dual displacement adapter to pump fluid through each of the first pump chamber and the second pump chamber in an alternating fashion, and
• wherein the pump chassis is sized and shaped to be manually supported by a user.