Hepatitis A virus preparation method and hepatitis A virus prepared according to method
AssigneeSK Bioscience Co., Ltd.
InventorsJung-eun Lee, Soo-young Kim, Seo Young Cho, Hun Kim, Kun Se Lee, Sujeen Lee
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Abstract
The present invention relates to a hepatitis A virus production method and hepatitis A virus produced according to the method, and, more specifically, to: a hepatitis A virus production method and hepatitis A virus produced according to the method, the method comprising the step of infecting a host cell with a virus obtained by transforming a host cell with a vector comprising an expression cassette, which comprises a hepatitis A virus gene, for hepatitis A virus preparation, and subculturing same.
Claims22
A hepatitis A virus gene defined by comprising SEQ ID NO:
- 1.
A method of preparing a hepatitis A vaccine, the method comprising steps of:
- (a) transfecting a host cell with a vector comprising an expression cassette comprising a hepatitis A virus gene of SEQ ID NO:
- 1;
- (b) obtaining a virus from the host cell of step (a);
- (c) infecting a host cell with the obtained virus from step (b) and subculturing the host cell;
- and
- (d) obtaining a virus from the host cell of step (c).
Dependencies are inferred from the claim text.