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US 12,558,147 B2Granted
Systems, devices, and methods for ablation using surgical clamps
AssigneeBoston Scientific Scimed, Inc.
InventorsRaju Viswanathan, Gary L. Long
Life of this patent
Estimating the term…
Abstract
Systems, devices, and methods for electroporation ablation therapy are disclosed, with the device including a first jaw including a plurality of first electrodes and a second jaw including a plurality of second electrodes. The first jaw and the second jaw may be substantially rigid, elongate, and collectively define a longitudinal axis. The first jaw and the second jaw may be configured to engage tissue therebetween during use.
Claims20
A method of ablating heart tissue at an atrial base of a pulmonary vein via irreversible electroporation, the method comprising:
- clamping the atrial base of the pulmonary vein between a first jaw and a second jaw of an ablation apparatus, the first jaw including a plurality of first electrodes, the second jaw including a plurality of second electrodes, the first jaw and the second jaw being substantially rigid, elongate, and collectively defining a longitudinal axis, each electrode of the plurality of first electrodes having, within a cross-section of the first jaw and the second jaw that is orthogonal to the longitudinal axis, a width that is less than a length of that electrode, the plurality of first electrodes spaced apart laterally with respect to the longitudinal axis, each electrode of the plurality of second electrodes having, within the cross-section orthogonal to the longitudinal axis, a width that is less than a length of that electrode, the plurality of second electrodes spaced apart laterally with respect to the longitudinal axis, wherein the first and second pluralities of electrodes are disposed directly across from each other in the cross-section orthogonal to the longitudinal axis;
- configuring an electrode of the plurality of first electrodes as an anode;
- configuring an electrode of the plurality of second electrodes as a cathode, the anode and the cathode being, within the cross-section orthogonal to the longitudinal axis, disposed diagonally across and spaced apart laterally from other another;
- and
- delivering ablative energy to the heart tissue via the anode and the cathode.
2 more elements
A method of ablating heart tissue at an atrial base of a pulmonary vein via irreversible electroporation, the method comprising:
- advancing an ablation apparatus to a location proximate the atrial base of the pulmonary vein, the ablation apparatus comprising a first jaw and a second jaw, the first jaw including a plurality of first electrodes arranged in parallel and spaced apart laterally along a length of the first jaw, the second jaw including a plurality of second electrodes arranged in parallel and spaced apart laterally along a length of the second jaw, the first jaw and the second jaw collectively defining a longitudinal axis, each electrode of the plurality of first electrodes having, within a cross-section of the first jaw and the second jaw that is orthogonal to the longitudinal axis, a width that is less than a length of that electrode, and each electrode of the plurality of second electrodes having, within the cross-section orthogonal to the longitudinal axis, a width that is less than a length of that electrode, the plurality of second electrodes spaced apart laterally with respect to the longitudinal axis, wherein the plurality of first electrodes are positioned in opposition the plurality of second electrode across the longitudinal axis;
- clamping the atrial base of the pulmonary vein between the first jaw and the second jaw of the ablation apparatus;
- configuring an electrode of the plurality of first electrodes as an anode;
- configuring an electrode of the plurality of second electrodes as a cathode, the anode and the cathode being, within the cross-section orthogonal to the longitudinal axis, disposed diagonally across and spaced apart laterally from other another;
- and
- delivering a pulse waveform to the heart tissue via the anode and the cathode.
3 more elements
A method of ablating heart tissue at an atrial base of a pulmonary vein via irreversible electroporation, the method comprising:
- advancing an ablation apparatus to a location proximate the atrial base of the pulmonary vein, the ablation apparatus comprising a first jaw and a second jaw, the first jaw including a plurality of first electrodes arranged in parallel and spaced apart laterally along a length of the first jaw, the second jaw including a plurality of second electrodes arranged in parallel and spaced apart laterally along a length of the second jaw, the first jaw and the second jaw collectively defining a longitudinal axis, each electrode of the plurality of first electrodes having, within a cross-section of the first jaw and the second jaw that is orthogonal to the longitudinal axis, a width that is less than a length of that electrode, and each electrode of the plurality of second electrodes having, within the cross-section orthogonal to the longitudinal axis, a width that is less than a length of that electrode, the plurality of second electrodes spaced apart laterally with respect to the longitudinal axis;
- clamping the atrial base of the pulmonary vein between the first jaw and the second jaw of the ablation apparatus;
- configuring an electrode of the plurality of first electrodes as an anode;
- configuring an electrode of the plurality of second electrodes as a cathode, the anode and the cathode being, within the cross-section orthogonal to the longitudinal axis, disposed diagonally across and spaced apart laterally from other another;
- and
- delivering a pacing signal to the heart via a pacing stimulator;
- and
- delivering a pulse waveform to the heart tissue via the anode and the cathode in synchronization with the pacing signal.
5 more elements
Dependencies are inferred from the claim text.