Non-invasive, uniform and non-uniform RF methods and systems related applications

A method of controlling an RF-based treatment system, the method comprising:

• selecting a length Y, wherein Y is a distance of signal transmission path from output of second node to an electrode of an electrode array or an input of applicator that incorporates the electrode array;
• connecting a plurality of nodes of the RF-based treatment system,
• wherein a first node controls one or more parameters of an RF drive signal;
• non-invasively contacting a skin surface with an electrode array;
• synchronizing a second node and a third node with the first node,
• wherein first node, second node and third node are in electrical communication with a radiofrequency (RF) transmission line,
• wherein the second node comprises distribution electronics and the third node comprises the electrode array,
• wherein each electrode of the electrode array is an individually addressable treatment electrode, the electrode array configured to direct RF energy for selective tissue coagulation,
• wherein the second node is configured to measure current flowing out of each electrode of the electrode array;
• transmitting control signals from first node to second node using serial communication protocol during an active treatment session,
• wherein the active treatment session is a non-ablative and non-invasive treatment session, wherein the electrode array is controlled to direct RF energy for non-ablative tissue treatment;
• measuring impedance values at one or more electrodes of the electrode array, within a region of tissue, during the active treatment session;
• determining impedance changes of tissue beneath skin surface under one or more electrodes of the electrode array using one or more of the measured impedance values within the region of tissue to obtain an impedance mapping of the region of tissue, wherein the signal transmission path having the length Y is a conductive trace on a printed circuit board, configured to improve the impedance mapping and reduce cross coupling below a threshold level,
• determining one or more temperatures of a tissue beneath the skin surface under one or more electrodes of the electrode array using the determined impedance changes,
• wherein the determined impedance changes are proportional to temperature changes in the tissue;
• and
• controlling activation and deactivation of a plurality of electrodes of the electrode array during the active treatment session to achieve substantially uniform treatment of the tissue region using the impedance mapping and the determined temperature in response to one or more determined temperatures.